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Discovery of Novel Tetrahydro-β-carboline Containing Aminopeptidase N Inhibitors as Cancer Chemosensitizers

Aminopeptidase N (APN, CD13) is closely associated with the development and progression of cancer. Previous studies suggested APN as a biomarker for cancer stem cells. APN inhibitors have been intensively evaluated as chemosensitizers for cancer treatments. In the present study, tetrahydro-β-carboli...

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Detalles Bibliográficos
Autores principales: Xing, Xiaoyan, Li, Fahui, Hu, Yajie, Zhang, Lin, Hui, Qian, Qin, Hongyu, Jiang, Qixiao, Jiang, Wenyan, Fang, Chunyan, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168271/
https://www.ncbi.nlm.nih.gov/pubmed/35677165
http://dx.doi.org/10.3389/fonc.2022.894842