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Empagliflozin restores cardiac metabolic flexibility in diet-induced obese C57BL6/J mice
Sodium-glucose co-transporter type 2 (SGLT2) inhibitor therapy to treat type 2 diabetes unexpectedly reduced all-cause mortality and hospitalization due to heart failure in several large-scale clinical trials, and has since been shown to produce similar cardiovascular disease-protective effects in p...
Autores principales: | Xie, Bingxian, Ramirez, Wesley, Mills, Amanda M., Huckestein, Brydie R., Anderson, Moira, Pangburn, Martha M., Lang, Eric Y., Mullet, Steven J., Chuan, Byron W., Guo, Lanping, Sipula, Ian, O'Donnell, Christopher P., Wendell, Stacy G., Scott, Iain, Jurczak, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168377/ https://www.ncbi.nlm.nih.gov/pubmed/35677213 http://dx.doi.org/10.1016/j.crphys.2022.05.003 |
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