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SREBP1 regulates Lgals3 activation in response to cholesterol loading

Aberrant smooth muscle cell (SMC) plasticity is etiological to vascular diseases. Cholesterol induces SMC phenotypic transition featuring high LGALS3 (galectin-3) expression. This proatherogenic process is poorly understood for its molecular underpinnings, in particular, the mechanistic role of ster...

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Detalles Bibliográficos
Autores principales:	Li, Jing, Shen, Hongtao, Owens, Gary K., Guo, Lian-Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168384/ https://www.ncbi.nlm.nih.gov/pubmed/35694209 http://dx.doi.org/10.1016/j.omtn.2022.05.028

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