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Oxygen microcapsules improve immune checkpoint blockade by ameliorating hypoxia condition in pancreatic ductal adenocarcinoma

RATIONALE: Hypoxia in tumor microenvironment (TME) represents an obstacle to the efficacy of immunotherapy for pancreatic ductal adenocarcinoma (PDAC) through several aspects such as increasing the expression of immune checkpoints or promoting fibrosis. Reversing hypoxic TME is a potential strategy...

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Detalles Bibliográficos
Autores principales:	Wu, Jiangchao, Wang, Xun, Chen, Li, Wang, Jianing, Zhang, Junlei, Tang, Jianghui, Ji, Yongtao, Song, Jinyuan, Wang, Lin, Zhao, Yaxing, Zhang, Hui, Li, Taohong, Sheng, Jianpeng, Chen, Dong, Zhang, Qi, Liang, Tingbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168385/ https://www.ncbi.nlm.nih.gov/pubmed/35702611 http://dx.doi.org/10.1016/j.bioactmat.2022.05.022

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