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An affordable implantable vagus nerve stimulator system for use in animal research
In this research, a vagus nerve stimulator has been developed and miniaturized for use in epilepsy research. The board contains all the components necessary for its operation during the standard duration of the experiments, being possible to control it once implanted and even being able to reuse it....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168444/ https://www.ncbi.nlm.nih.gov/pubmed/35658680 http://dx.doi.org/10.1098/rsta.2021.0010 |
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author | Canal-Alonso, Ángel Casado-Vara, Roberto Castellano, Orlando Herrera-Santos, Jorge Gonçalves, Jaime Màrquez-Sànchez, Sergio Gonçalves, Jesús María Corchado, Juan Manuel |
author_facet | Canal-Alonso, Ángel Casado-Vara, Roberto Castellano, Orlando Herrera-Santos, Jorge Gonçalves, Jaime Màrquez-Sànchez, Sergio Gonçalves, Jesús María Corchado, Juan Manuel |
author_sort | Canal-Alonso, Ángel |
collection | PubMed |
description | In this research, a vagus nerve stimulator has been developed and miniaturized for use in epilepsy research. The board contains all the components necessary for its operation during the standard duration of the experiments, being possible to control it once implanted and even being able to reuse it. The VNS system has been designed for rodents since the VNS devices available for human are not only too large for laboratory animals, but also too expensive. With this solution the expenditure on materials made by laboratories is greatly reduced and bioethical considerations were kept in mind. The system was validated in hamsters. This article is part of the theme issue ‘Advanced neurotechnologies: translating innovation for health and well-being’. |
format | Online Article Text |
id | pubmed-9168444 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-91684442022-06-12 An affordable implantable vagus nerve stimulator system for use in animal research Canal-Alonso, Ángel Casado-Vara, Roberto Castellano, Orlando Herrera-Santos, Jorge Gonçalves, Jaime Màrquez-Sànchez, Sergio Gonçalves, Jesús María Corchado, Juan Manuel Philos Trans A Math Phys Eng Sci Articles In this research, a vagus nerve stimulator has been developed and miniaturized for use in epilepsy research. The board contains all the components necessary for its operation during the standard duration of the experiments, being possible to control it once implanted and even being able to reuse it. The VNS system has been designed for rodents since the VNS devices available for human are not only too large for laboratory animals, but also too expensive. With this solution the expenditure on materials made by laboratories is greatly reduced and bioethical considerations were kept in mind. The system was validated in hamsters. This article is part of the theme issue ‘Advanced neurotechnologies: translating innovation for health and well-being’. The Royal Society 2022-07-25 2022-06-06 /pmc/articles/PMC9168444/ /pubmed/35658680 http://dx.doi.org/10.1098/rsta.2021.0010 Text en © 2022 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Articles Canal-Alonso, Ángel Casado-Vara, Roberto Castellano, Orlando Herrera-Santos, Jorge Gonçalves, Jaime Màrquez-Sànchez, Sergio Gonçalves, Jesús María Corchado, Juan Manuel An affordable implantable vagus nerve stimulator system for use in animal research |
title | An affordable implantable vagus nerve stimulator system for use in animal research |
title_full | An affordable implantable vagus nerve stimulator system for use in animal research |
title_fullStr | An affordable implantable vagus nerve stimulator system for use in animal research |
title_full_unstemmed | An affordable implantable vagus nerve stimulator system for use in animal research |
title_short | An affordable implantable vagus nerve stimulator system for use in animal research |
title_sort | affordable implantable vagus nerve stimulator system for use in animal research |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168444/ https://www.ncbi.nlm.nih.gov/pubmed/35658680 http://dx.doi.org/10.1098/rsta.2021.0010 |
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