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Carbon sources and pathways for citrate secreted by human prostate cancer cells determined by NMR tracing and metabolic modeling
Prostate epithelial cells have the unique capacity to secrete large amounts of citrate, but the carbon sources and metabolic pathways that maintain this production are not well known. We mapped potential pathways for citrate carbons in the human prostate cancer metastasis cell lines LNCaP and VCaP,...
Autores principales: | van Heijster, Frits H. A., Breukels, Vincent, Jansen, Kees (C.) F. J., Schalken, Jack A., Heerschap, Arend |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168453/ https://www.ncbi.nlm.nih.gov/pubmed/35353621 http://dx.doi.org/10.1073/pnas.2024357119 |
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