CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation

The receptor for colony stimulating factor 1 (CSF-1R) is important for the survival and function of myeloid cells that mediate pathology during experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). CSF-1 and IL-34, the ligands of CSF-1R, have similar bioactivit...

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Detalles Bibliográficos
Autores principales: Hwang, Daniel, Seyedsadr, Maryam S., Ishikawa, Larissa Lumi Watanabe, Boehm, Alexandra, Sahin, Ziver, Casella, Giacomo, Jang, Soohwa, Gonzalez, Michael V., Garifallou, James P., Hakonarson, Hakon, Zhang, Weifeng, Xiao, Dan, Rostami, Abdolmohamad, Zhang, Guang-Xian, Ciric, Bogoljub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168454/
https://www.ncbi.nlm.nih.gov/pubmed/35353625
http://dx.doi.org/10.1073/pnas.2111804119

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