A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are initiated by attachment of the receptor-binding domain (RBD) on the viral Spike protein to angiotensin-converting enzyme-2 (ACE2) on human host cells. This critical first step occurs in dynamic environments, where external f...

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Detalles Bibliográficos
Autores principales: Bauer, Magnus S., Gruber, Sophia, Hausch, Adina, Gomes, Priscila S. F. C., Milles, Lukas F., Nicolaus, Thomas, Schendel, Leonard C., Navajas, Pilar López, Procko, Erik, Lietha, Daniel, Melo, Marcelo C. R., Bernardi, Rafael C., Gaub, Hermann E., Lipfert, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168514/
https://www.ncbi.nlm.nih.gov/pubmed/35312342
http://dx.doi.org/10.1073/pnas.2114397119
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