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Protein cost minimization promotes the emergence of coenzyme redundancy

Coenzymes distribute a variety of chemical moieties throughout cellular metabolism, participating in group (e.g., phosphate and acyl) and electron transfer. For a variety of reactions requiring acceptors or donors of specific resources, there often exist degenerate sets of molecules [e.g., NAD(H) an...

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Detalles Bibliográficos
Autores principales: Goldford, Joshua E., George, Ashish B., Flamholz, Avi I., Segrè, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168515/
https://www.ncbi.nlm.nih.gov/pubmed/35344442
http://dx.doi.org/10.1073/pnas.2110787119