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Protein cost minimization promotes the emergence of coenzyme redundancy
Coenzymes distribute a variety of chemical moieties throughout cellular metabolism, participating in group (e.g., phosphate and acyl) and electron transfer. For a variety of reactions requiring acceptors or donors of specific resources, there often exist degenerate sets of molecules [e.g., NAD(H) an...
Autores principales: | Goldford, Joshua E., George, Ashish B., Flamholz, Avi I., Segrè, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168515/ https://www.ncbi.nlm.nih.gov/pubmed/35344442 http://dx.doi.org/10.1073/pnas.2110787119 |
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