Multiple Primary Lung Cancers With ALK Rearrangement: A Case Report and Literature Review

Multiple primary lung cancers (MPLCs) are that patients with lung cancer may present with two primary tumors at the same time (synchronous multiple primary lung cancer, SMPLC) or may develop a second, metachronous primary lung cancer after treatment of the initial lesion. Currently, there are no def...

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Autores principales: Huimin, Zhou, Xueting, Wang, Qi, Qi, Lingxin, Feng, Xue, Yang, Zhuang, Yu, Jing, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168597/
https://www.ncbi.nlm.nih.gov/pubmed/35677159
http://dx.doi.org/10.3389/fonc.2022.897451
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author Huimin, Zhou
Xueting, Wang
Qi, Qi
Lingxin, Feng
Xue, Yang
Zhuang, Yu
Jing, Wang
author_facet Huimin, Zhou
Xueting, Wang
Qi, Qi
Lingxin, Feng
Xue, Yang
Zhuang, Yu
Jing, Wang
author_sort Huimin, Zhou
collection PubMed
description Multiple primary lung cancers (MPLCs) are that patients with lung cancer may present with two primary tumors at the same time (synchronous multiple primary lung cancer, SMPLC) or may develop a second, metachronous primary lung cancer after treatment of the initial lesion. Currently, there are no definitive guidelines for the diagnosis and treatment of multiple primary lung cancers. Herein, we report a case of double primary lung cancers with ALK rearrangement. The patient was treated with chemotherapy, targeted therapy, and radiotherapy. After these treatments, the patient was free of locally recurrent or distant disease at 2 years.
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spelling pubmed-91685972022-06-07 Multiple Primary Lung Cancers With ALK Rearrangement: A Case Report and Literature Review Huimin, Zhou Xueting, Wang Qi, Qi Lingxin, Feng Xue, Yang Zhuang, Yu Jing, Wang Front Oncol Oncology Multiple primary lung cancers (MPLCs) are that patients with lung cancer may present with two primary tumors at the same time (synchronous multiple primary lung cancer, SMPLC) or may develop a second, metachronous primary lung cancer after treatment of the initial lesion. Currently, there are no definitive guidelines for the diagnosis and treatment of multiple primary lung cancers. Herein, we report a case of double primary lung cancers with ALK rearrangement. The patient was treated with chemotherapy, targeted therapy, and radiotherapy. After these treatments, the patient was free of locally recurrent or distant disease at 2 years. Frontiers Media S.A. 2022-05-23 /pmc/articles/PMC9168597/ /pubmed/35677159 http://dx.doi.org/10.3389/fonc.2022.897451 Text en Copyright © 2022 Huimin, Xueting, Qi, Lingxin, Xue, Zhuang and Jing https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Huimin, Zhou
Xueting, Wang
Qi, Qi
Lingxin, Feng
Xue, Yang
Zhuang, Yu
Jing, Wang
Multiple Primary Lung Cancers With ALK Rearrangement: A Case Report and Literature Review
title Multiple Primary Lung Cancers With ALK Rearrangement: A Case Report and Literature Review
title_full Multiple Primary Lung Cancers With ALK Rearrangement: A Case Report and Literature Review
title_fullStr Multiple Primary Lung Cancers With ALK Rearrangement: A Case Report and Literature Review
title_full_unstemmed Multiple Primary Lung Cancers With ALK Rearrangement: A Case Report and Literature Review
title_short Multiple Primary Lung Cancers With ALK Rearrangement: A Case Report and Literature Review
title_sort multiple primary lung cancers with alk rearrangement: a case report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168597/
https://www.ncbi.nlm.nih.gov/pubmed/35677159
http://dx.doi.org/10.3389/fonc.2022.897451
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