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Activation of PI3K/p110α in the Lung Mesenchyme Affects Branching Morphogenesis and Club Cell Differentiation

Epithelial–mesenchymal interaction is required for normal growth, morphogenetic patterning, and cellular differentiation in developing lungs. Various signaling pathways have been defined in establishing the patterning of this branched organ. The phosphoinositide-3-kinase (PI3K) signaling plays an im...

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Detalles Bibliográficos
Autores principales: Dai, Haiting, Zhu, Mingli, Li, Wenya, Si, Guohui, Xing, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168599/
https://www.ncbi.nlm.nih.gov/pubmed/35676931
http://dx.doi.org/10.3389/fcell.2022.880206