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High frequency repetitive transcranial magnetic stimulation alleviates cognitive deficits in 3xTg-AD mice by modulating the PI3K/Akt/GLT-1 Axis

OBJECTIVE: Glutamate mediated excitotoxicity, such as oxidative stress, neuroinflammation, synaptic loss and neuronal death, is ubiquitous in Alzheimer's disease (AD). Our previous study found that 15 Hz repetitive transcranial magnetic stimulation (rTMS) could reduce cortical excitability. The...

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Detalles Bibliográficos
Autores principales: Cao, Huan, Zuo, Chengchao, Gu, Zhongya, Huang, Yaqi, Yang, Yuyan, Zhu, Liudi, Jiang, Yongsheng, Wang, Furong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168605/
https://www.ncbi.nlm.nih.gov/pubmed/35660628
http://dx.doi.org/10.1016/j.redox.2022.102354