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High frequency repetitive transcranial magnetic stimulation alleviates cognitive deficits in 3xTg-AD mice by modulating the PI3K/Akt/GLT-1 Axis
OBJECTIVE: Glutamate mediated excitotoxicity, such as oxidative stress, neuroinflammation, synaptic loss and neuronal death, is ubiquitous in Alzheimer's disease (AD). Our previous study found that 15 Hz repetitive transcranial magnetic stimulation (rTMS) could reduce cortical excitability. The...
Autores principales: | Cao, Huan, Zuo, Chengchao, Gu, Zhongya, Huang, Yaqi, Yang, Yuyan, Zhu, Liudi, Jiang, Yongsheng, Wang, Furong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168605/ https://www.ncbi.nlm.nih.gov/pubmed/35660628 http://dx.doi.org/10.1016/j.redox.2022.102354 |
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