Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease

Picornaviruses are small RNA viruses that hijack host cell machinery to promote their replication. During infection, these viruses express two proteases, 2A(pro) and 3C(pro), which process viral proteins. They also subvert a number of host functions, including innate immune responses, host protein s...

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Detalles Bibliográficos
Autores principales: Serganov, Artem A., Udi, Yael, Stein, Milana E., Patel, Valay, Fridy, Peter C., Rice, Charles M., Saeed, Mohsan, Jacobs, Erica Y., Chait, Brian T., Rout, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168619/
https://www.ncbi.nlm.nih.gov/pubmed/35367208
http://dx.doi.org/10.1016/j.jbc.2022.101882

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