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Rational Design of P450 aMOx for Improving Anti-Markovnikov Selectivity Based on the “Butterfly” Model

Aromatic aldehydes are important industrial raw materials mainly synthesized by anti-Markovnikov (AM) oxidation of corresponding aromatic olefins. The AM product selectivity remains a big challenge. P450 aMOx is the first reported enzyme that could catalyze AM oxidation of aromatic olefins. Here, we...

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Detalles Bibliográficos
Autores principales: Pan, Yue, Bao, Jinxiao, Zhang, Xingyi, Ni, Hui, Zhao, Yue, Zhi, Fengdong, Fang, Bohuan, He, Xiao, Zhang, John Z. H., Zhang, Lujia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168652/
https://www.ncbi.nlm.nih.gov/pubmed/35677881
http://dx.doi.org/10.3389/fmolb.2022.888721