Cargando…

Silencing PLOD2 attenuates cancer stem cell-like characteristics and cisplatin-resistant through Integrin β1 in laryngeal cancer

Laryngeal cancer (LC) is an aggressive malignancy resistant to drug treatments. It has been postulated that cancer stem cells (CSCs) persist in a unique population of cancer cells involved in tumor progression and drug-resistance. In the present study, the effects of PLOD2 expression on ordinary and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Meiyan, Liu, Xing, Li, Tao, Zhang, Yueqin, Zhao, Xiaoyan, Sun, Wen, Li, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168686/ https://www.ncbi.nlm.nih.gov/pubmed/35660870 http://dx.doi.org/10.1016/j.tranon.2022.101460

Ejemplares similares

PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer stem cell-like characteristics
por: Sheng, Xiaoli, et al.
Publicado: (2019)

PB1798: EVALUATION OF EXPRESSION OF PLODS FAMILY GENES (PLOD1, PLOD2, PLOD3) IN PATIENTS WITH ACUTE MYELOID LEUKEMIA
por: Zaker, F., et al.
Publicado: (2022)

PLOD2 Is Essential to Functional Activation of Integrin β1 for Invasion/Metastasis in Head and Neck Squamous Cell Carcinomas
por: Ueki, Yushi, et al.
Publicado: (2020)

Roles of PLODs in Collagen Synthesis and Cancer Progression
por: Qi, Yifei, et al.
Publicado: (2018)

COLGALT2 is overexpressed in ovarian cancer and interacts with PLOD3
por: Guo, Ting, et al.
Publicado: (2021)

KRAB-Induced Heterochromatin Effectively Silences PLOD2 Gene Expression in Somatic Cells and Is Resilient to TGFβ1 Activation
por: Gjaltema, Rutger A. F., et al.
Publicado: (2020)

Integrin β1 regulates the invasion and radioresistance of laryngeal cancer cells by targeting CD147
por: Li, Li, et al.
Publicado: (2018)

Overexpressing PLOD family genes predict poor prognosis in gastric cancer
por: Li, Shan-Shan, et al.
Publicado: (2020)

PLOD2 high expression associates with immune infiltration and facilitates cancer progression in osteosarcoma
por: Wang, Zhen, et al.
Publicado: (2022)

Overexpressing PLOD Family Genes Predict Poor Prognosis in Pancreatic Cancer
por: Zhang, Jing, et al.
Publicado: (2022)

Pan-Cancer Analyses Reveal Oncogenic and Immunological Role of PLOD2
por: Xu, Qiqi, et al.
Publicado: (2022)

PLOD2 Is a Potent Prognostic Marker and Associates with Immune Infiltration in Cervical Cancer
por: Li, Guang, et al.
Publicado: (2021)

Bioinformatic analysis of PLOD family member expression and prognostic value in non-small cell lung cancer
por: Qi, Qi, et al.
Publicado: (2021)

The PLOD2/succinate axis regulates the epithelial–mesenchymal plasticity and cancer cell stemness
por: Tong, Yuxin, et al.
Publicado: (2023)

PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1
por: Saito, Ken, et al.
Publicado: (2021)

Comprehensive Analysis of the Expression, Prognosis, and Biological Significance of PLOD Family in Bladder Cancer
por: Chen, Ru, et al.
Publicado: (2023)

Corrigendum to “PLOD2 Is a Potent Prognostic Marker and Associates with Immune Infiltration in Cervical Cancer”
por: Li, Guang, et al.
Publicado: (2021)

Proteomics profiling of colorectal cancer progression identifies PLOD2 as a potential therapeutic target
por: Shao, Yingkuan, et al.
Publicado: (2021)

Characterisation of the Drosophila procollagen lysyl hydroxylase, dPlod
por: Bunt, Stephanie, et al.
Publicado: (2011)

Expression and Prognostic Role of PLOD1 in Malignant Glioma
por: Wang, Hao, et al.
Publicado: (2020)

Dysregulation of PLOD2 Promotes Tumor Metastasis and Invasion in Hepatocellular Carcinoma
por: Li, Keren, et al.
Publicado: (2023)

RNA silencing of integrin-linked kinase increases the sensitivity of the A549 lung cancer cell line to cisplatin and promotes its apoptosis
por: ZHAO, XIAOZHEN, et al.
Publicado: (2015)

Integrated Profiling Identifies PLOD3 as a Potential Prognostic and Immunotherapy Relevant Biomarker in Colorectal Cancer
por: Shi, Junhong, et al.
Publicado: (2021)

Identification of PLOD3 and LRRN3 as potential biomarkers for Parkinson’s disease based on integrative analysis
por: Guo, Xing, et al.
Publicado: (2023)

MYC Suppresses Cancer Metastasis by Direct Transcriptional Silencing of αv and β3 Integrin Subunits
por: Liu, Hong, et al.
Publicado: (2012)

Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β-catenin silencing
por: Zhu, Xidan, et al.
Publicado: (2020)

Silencing of CD276 suppresses lung cancer progression by regulating integrin signaling
por: Li, Fang, et al.
Publicado: (2020)

Overexpression of PLOD3 promotes tumor progression and poor prognosis in gliomas
por: Tsai, Chia-Kuang, et al.
Publicado: (2018)

CircRNA PLOD2 enhances ovarian cancer propagation by controlling miR-378
por: Wei, Xiaoqiang, et al.
Publicado: (2021)

The characteristics and the multiple functions of integrin β1 in human cancers
por: Sun, Li, et al.
Publicado: (2023)

Clinical Prognostic Value of the PLOD Gene Family in Lung Adenocarcinoma
por: Meng, Yiming, et al.
Publicado: (2022)

Silencing of NLRP3 Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin
por: Li, Weijia, et al.
Publicado: (2023)

Novel Mutations in FKBP10 and PLOD2 Cause Rare Bruck Syndrome in Chinese Patients
por: Zhou, Peiran, et al.
Publicado: (2014)

Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins
por: Zhong, Banghua, et al.
Publicado: (2018)

PLOD3 Is Associated with Immune Cell Infiltration and Genomic Instability in Colon Adenocarcinoma
por: Deng, Xianyu, et al.
Publicado: (2021)

Silencing salusin-β attenuates cardiovascular remodeling and hypertension in spontaneously hypertensive rats
por: Ren, Xing-Sheng, et al.
Publicado: (2017)

PLOD2 increases resistance of gastric cancer cells to 5-fluorouracil by upregulating BCRP and inhibiting apoptosis
por: Wang, Xiaohui, et al.
Publicado: (2020)

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin
por: Liang, Sixian, et al.
Publicado: (2014)

Aberrantly expressed PLOD1 promotes cancer aggressiveness in bladder cancer: a potential prognostic marker and therapeutic target
por: Yamada, Yasutaka, et al.
Publicado: (2019)

PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC
por: Du, Hongzhi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_632kgasc9qid3fi9n8sv9h6d31