Analysis of functional surfaces on the actin nucleation promoting factor Dip1 required for Arp2/3 complex activation and endocytic actin network assembly

Arp2/3 complex nucleates branched actin filaments that drive processes like endocytosis and lamellipodial protrusion. WISH/DIP/SPIN90 (WDS) proteins form a class of Arp2/3 complex activators or nucleation promoting factors (NPFs) that, unlike WASP family NPFs, activate Arp2/3 complex without requiri...

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Detalles Bibliográficos
Autores principales: Liu, Su-Ling, Narvaez-Ortiz, Heidy Y., Miner, Matt, Kiemel, Jack, Oberhelman, Nicholas, Watt, April, Wagner, Andrew R., Luan, Qing, Helgeson, Luke A., Nolen, Brad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168731/
https://www.ncbi.nlm.nih.gov/pubmed/35533728
http://dx.doi.org/10.1016/j.jbc.2022.102019

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