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Inhibition of Human Prostate and Bladder Smooth Muscle Contraction, Vasoconstriction of Porcine Renal and Coronary Arteries, and Growth-Related Functions of Prostate Stromal Cells by Presumed Small Molecule Gα(q/11) Inhibitor, YM-254890

Introduction: Lower urinary tract symptoms (LUTS) involve benign prostatic hyperplasia (BPH) and overactive bladder (OAB). Standard-of-care medical treatment includes α(1)-blockers and antimuscarinics for reduction of prostate and detrusor smooth muscle tone, respectively, and 5α-reductase inhibitor...

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Detalles Bibliográficos
Autores principales:	Tamalunas, Alexander, Wendt, Amin, Springer, Florian, Ciotkowska, Anna, Rutz, Beata, Wang, Ruixiao, Huang, Ru, Liu, Yuhan, Schulz, Heiko, Ledderose, Stephan, Magistro, Giuseppe, Stief, Christian G., Hennenberg, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168773/ https://www.ncbi.nlm.nih.gov/pubmed/35677088 http://dx.doi.org/10.3389/fphys.2022.884057

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