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Inhibition of Human Prostate and Bladder Smooth Muscle Contraction, Vasoconstriction of Porcine Renal and Coronary Arteries, and Growth-Related Functions of Prostate Stromal Cells by Presumed Small Molecule Gα(q/11) Inhibitor, YM-254890
Introduction: Lower urinary tract symptoms (LUTS) involve benign prostatic hyperplasia (BPH) and overactive bladder (OAB). Standard-of-care medical treatment includes α(1)-blockers and antimuscarinics for reduction of prostate and detrusor smooth muscle tone, respectively, and 5α-reductase inhibitor...
Autores principales: | Tamalunas, Alexander, Wendt, Amin, Springer, Florian, Ciotkowska, Anna, Rutz, Beata, Wang, Ruixiao, Huang, Ru, Liu, Yuhan, Schulz, Heiko, Ledderose, Stephan, Magistro, Giuseppe, Stief, Christian G., Hennenberg, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168773/ https://www.ncbi.nlm.nih.gov/pubmed/35677088 http://dx.doi.org/10.3389/fphys.2022.884057 |
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