Bleeding During Veno-Venous ECMO: Prevention and Treatment

Veno-venous extracorporeal membrane oxygenation (vvECMO) has become a routine treatment for severe lung failure in specialized centers. Spontaneous bleeding complications, however, are observed in 30–60% of patients during vvECMO treatment. Bleeding increases mortality by factors 2–3. Anticoagulatio...

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Detalles Bibliográficos
Autores principales: Kalbhenn, Johannes, Zieger, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168900/
https://www.ncbi.nlm.nih.gov/pubmed/35677828
http://dx.doi.org/10.3389/fmed.2022.879579
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author Kalbhenn, Johannes
Zieger, Barbara
author_facet Kalbhenn, Johannes
Zieger, Barbara
author_sort Kalbhenn, Johannes
collection PubMed
description Veno-venous extracorporeal membrane oxygenation (vvECMO) has become a routine treatment for severe lung failure in specialized centers. Spontaneous bleeding complications, however, are observed in 30–60% of patients during vvECMO treatment. Bleeding increases mortality by factors 2–3. Anticoagulation in combination with several acquired bleeding disorders caused by the mechanical pump and the foreign layer of the extracorporeal system contribute to the risk of bleeding. In this review, the mechanisms of the underlying pathologies and the route from diagnosis to treatment are described.
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spelling pubmed-91689002022-06-07 Bleeding During Veno-Venous ECMO: Prevention and Treatment Kalbhenn, Johannes Zieger, Barbara Front Med (Lausanne) Medicine Veno-venous extracorporeal membrane oxygenation (vvECMO) has become a routine treatment for severe lung failure in specialized centers. Spontaneous bleeding complications, however, are observed in 30–60% of patients during vvECMO treatment. Bleeding increases mortality by factors 2–3. Anticoagulation in combination with several acquired bleeding disorders caused by the mechanical pump and the foreign layer of the extracorporeal system contribute to the risk of bleeding. In this review, the mechanisms of the underlying pathologies and the route from diagnosis to treatment are described. Frontiers Media S.A. 2022-05-23 /pmc/articles/PMC9168900/ /pubmed/35677828 http://dx.doi.org/10.3389/fmed.2022.879579 Text en Copyright © 2022 Kalbhenn and Zieger. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Kalbhenn, Johannes
Zieger, Barbara
Bleeding During Veno-Venous ECMO: Prevention and Treatment
title Bleeding During Veno-Venous ECMO: Prevention and Treatment
title_full Bleeding During Veno-Venous ECMO: Prevention and Treatment
title_fullStr Bleeding During Veno-Venous ECMO: Prevention and Treatment
title_full_unstemmed Bleeding During Veno-Venous ECMO: Prevention and Treatment
title_short Bleeding During Veno-Venous ECMO: Prevention and Treatment
title_sort bleeding during veno-venous ecmo: prevention and treatment
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168900/
https://www.ncbi.nlm.nih.gov/pubmed/35677828
http://dx.doi.org/10.3389/fmed.2022.879579
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