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Systemic Immune Dysregulation in Early Breast Cancer Is Associated With Decreased Plasma Levels of Both Soluble Co-Inhibitory and Co-Stimulatory Immune Checkpoint Molecules
Breast cancer cells exploit the up-regulation or down-regulation of immune checkpoint proteins to evade anti-tumor immune responses. To explore the possible involvement of this mechanism in promoting systemic immunosuppression, the pre-treatment levels of soluble co-inhibitory and co-stimulatory imm...
Autores principales: | Rapoport, Bernardo L., Steel, Helen C., Hlatshwayo, Nomsa, Theron, Annette J., Meyer, Pieter W. A., Nayler, Simon, Benn, Carol-Ann, Smit, Teresa, Kwofie, Luyanda L. I., Heyman, Liezl, Anderson, Ronald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168983/ https://www.ncbi.nlm.nih.gov/pubmed/35677046 http://dx.doi.org/10.3389/fimmu.2022.823842 |
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