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Target identification and occupancy measurement of necrosis avid agent rhein using bioorthogonal chemistry-enabling probes

Necrosis is an important biomarker, which only occurs in pathological situations. Tracking of necrosis avid agents is of crucial importance toward understanding their mechanisms. Herein, we developed a modular probe strategy based on bioorthogonal copper-free click chemistry. Structural modification...

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Detalles Bibliográficos
Autores principales: Jiang, Cuihua, Zhang, Jian, Hu, Shihe, Gao, Meng, Zhang, Dongjian, Yao, Nan, Jin, Qiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169075/
https://www.ncbi.nlm.nih.gov/pubmed/35754899
http://dx.doi.org/10.1039/d2ra02844a