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Target identification and occupancy measurement of necrosis avid agent rhein using bioorthogonal chemistry-enabling probes
Necrosis is an important biomarker, which only occurs in pathological situations. Tracking of necrosis avid agents is of crucial importance toward understanding their mechanisms. Herein, we developed a modular probe strategy based on bioorthogonal copper-free click chemistry. Structural modification...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169075/ https://www.ncbi.nlm.nih.gov/pubmed/35754899 http://dx.doi.org/10.1039/d2ra02844a |