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Accurate reconstruction of viral genomes in human cells from short reads using iterative refinement

BACKGROUND: After an infection, human cells may contain viral genomes in the form of episomes or integrated DNA. Comparing the genomic sequences of different strains of a virus in human cells can often provide useful insights into its behaviour, activity and pathology, and may help develop methods f...

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Detalles Bibliográficos
Autores principales: Lee, Sau-Dan, Wu, Man, Lo, Kwok-Wai, Yip, Kevin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169298/
https://www.ncbi.nlm.nih.gov/pubmed/35668367
http://dx.doi.org/10.1186/s12864-022-08649-8