Cargando…

Grafted human ESC-derived astroglia repair spinal cord injury via activation of host anti-inflammatory microglia in the lesion area

Grafted astroglia/astrocytes exhibit neuroprotective effects and improve functional recovery after injury to the central nervous system. This study sought to elucidate their ability to repair spinal cord lesions and the underlying mechanisms. Methods: Complete spinal transection, transplantation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jian, Jiang, Peng, Deng, Wenbin, Sun, Yuhui, Liu, Yaobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169351/ https://www.ncbi.nlm.nih.gov/pubmed/35673563 http://dx.doi.org/10.7150/thno.70929

Ejemplares similares

hESC-derived Olig2(+) progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury
por: Jiang, Peng, et al.
Publicado: (2013)

Astroglia-Microglia Cross Talk during Neurodegeneration in the Rat Hippocampus
por: Batlle, Montserrat, et al.
Publicado: (2015)

Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination
por: Une, Hayato, et al.
Publicado: (2021)

Glial alterations in human prion diseases: A correlative study of astroglia, reactive microglia, protein deposition, and neuropathological lesions
por: Monzón, Marta, et al.
Publicado: (2018)

Proliferation in the Alzheimer Hippocampus Is due to Microglia, Not Astroglia, and Occurs at Sites of Amyloid Deposition
por: Marlatt, Michael W., et al.
Publicado: (2014)

Neonatal microglia-organized scar-free spinal cord repair
por: Li, Yi, et al.
Publicado: (2020)

Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
por: Fellner, Lisa, et al.
Publicado: (2013)

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia
por: Chucair-Elliott, Ana J., et al.
Publicado: (2020)

Microglia and Astroglia—The Potential Role in Neuroinflammation Induced by Pre- and Neonatal Exposure to Lead (Pb)
por: Gąssowska-Dobrowolska, Magdalena, et al.
Publicado: (2023)

Microglia coordinate cellular interactions during spinal cord repair in mice
por: Brennan, Faith H., et al.
Publicado: (2022)

The role of astroglia in neuroprotection
por: Bélanger, Mireille, et al.
Publicado: (2009)

Trophic support following peripheral axotomy show different behaviour of reactive microglia and astroglia in the ventral horn
por: Papa, Michele, et al.
Publicado: (2015)

SERPINA3 induced by astroglia/microglia co-culture facilitates glioblastoma stem-like cell invasion
por: Li, Yang, et al.
Publicado: (2018)

Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum
por: Nazari, Zahra, et al.
Publicado: (2022)

Microglia in the spinal cord and neuropathic pain
por: Tsuda, Makoto
Publicado: (2015)

Differences of Microglia in the Brain and the Spinal Cord
por: Xuan, Fang-Ling, et al.
Publicado: (2019)

Spinal Cord Microglia in Health and Disease
por: Kolos, E. A., et al.
Publicado: (2020)

The Role of Astroglia in the Epileptic Brain
por: Losi, Gabriele, et al.
Publicado: (2012)

Memory Formation Shaped by Astroglia
por: Zorec, Robert, et al.
Publicado: (2015)

Astroglia and Tau: New Perspectives
por: Kovacs, Gabor G.
Publicado: (2020)

Astroglia in Sepsis Associated Encephalopathy
por: Shulyatnikova, Tatyana, et al.
Publicado: (2019)

Astroglia in Autism Spectrum Disorder
por: Gzielo, Kinga, et al.
Publicado: (2021)

Differential suppression of interferon-γ-induced Ia antigen expression on cultured rat astroglia and microglia by second messengers()
por: Sasaki, Atsushi, et al.
Publicado: (1990)

A role for astroglia in prion diseases
por: Aguzzi, Adriano, et al.
Publicado: (2017)

Emerging Roles of Microglia Depletion in the Treatment of Spinal Cord Injury
por: Deng, Junhao, et al.
Publicado: (2022)

Intramedullary spinal cord lesions in an immunocompromised host due to Mycobacterium haemophilum
por: Kon, Shelley, et al.
Publicado: (2019)

The mutual interaction between the host spinal cord and grafted undifferentiated stem cells fosters the production of a lesion-induced secretome
por: Pajer, Krisztián, et al.
Publicado: (2020)

Two Faces of Chondroitin Sulfate Proteoglycan in Spinal Cord Repair: A Role in Microglia/Macrophage Activation
por: Rolls, Asya, et al.
Publicado: (2008)

Microglia and Spinal Cord Synaptic Plasticity in Persistent Pain
por: Taves, Sarah, et al.
Publicado: (2013)

Current Knowledge of Microglia in Traumatic Spinal Cord Injury
por: Xu, Lintao, et al.
Publicado: (2022)

Transplantation of Microglia in the Area of Spinal Cord Injury in an Acute Period Increases Tissue Sparing, but Not Functional Recovery
por: Akhmetzyanova, Elvira R., et al.
Publicado: (2018)

Advancing Peripheral Nerve Graft Transplantation for Incomplete Spinal Cord Injury Repair
por: Kjell, Jacob, et al.
Publicado: (2022)

Effects of a solid lipid curcumin particle formulation on chronic activation of microglia and astroglia in the GFAP-IL6 mouse model
por: Ullah, Faheem, et al.
Publicado: (2020)

Morphological plasticity of astroglia: Understanding synaptic microenvironment
por: Heller, Janosch P., et al.
Publicado: (2015)

Altered oligodendroglia and astroglia in chronic traumatic encephalopathy
por: Chancellor, K. Blake, et al.
Publicado: (2021)

A Star is Born: Newborn Astroglia in Epilepsy
por: Dang, Louis T.
Publicado: (2022)

IL-1 Mediates Chronic Stress-Induced Hyperalgesia Accompanied by Microglia and Astroglia Morphological Changes in Pain-Related Brain Regions in Mice
por: Fülöp, Barbara, et al.
Publicado: (2023)

The Role of Microglia in Modulating Neuroinflammation after Spinal Cord Injury
por: Brockie, Sydney, et al.
Publicado: (2021)

Severity- and Time-Dependent Activation of Microglia in Spinal Cord Injury
por: Akhmetzyanova, Elvira Ruslanovna, et al.
Publicado: (2023)

Cocaine potentiates an inflammatory response in C6 astroglia-like cells
por: Agharahimi, Maryam, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7a9itjde55lgmha31odeh8e518