The role of Jagged1 as a dynamic switch of cancer cell plasticity in PDAC assembloids

Background: Pancreatic ductal adenocarcinoma (PDAC), which commonly relapses due to chemotherapy resistance, has a poor 5-year survival rate (< 10%). The ability of PDAC to dynamically switch between cancer-initiating cell (CIC) and non-CIC states, which is influenced by both internal and externa...

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Detalles Bibliográficos
Autores principales: Choi, Jae-Il, Rim, John Hoon, Jang, Sung Ill, Park, Joon Seong, Park, Hak, Cho, Jae Hee, Lim, Jong-Baeck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169352/
https://www.ncbi.nlm.nih.gov/pubmed/35673567
http://dx.doi.org/10.7150/thno.71364

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