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K(Na)1.1 gain-of-function preferentially dampens excitability of murine parvalbumin-positive interneurons

KCNT1 encodes the sodium-activated potassium channel K(Na)1.1, expressed preferentially in the frontal cortex, hippocampus, cerebellum, and brainstem. Pathogenic missense variants in KCNT1 are associated with intractable epilepsy, namely epilepsy of infancy with migrating focal seizures (EIMFS), and...

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Detalles Bibliográficos
Autores principales:	Gertler, Tracy S., Cherian, Suraj, DeKeyser, Jean-Marc, Kearney, Jennifer A., George, Alfred L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169414/ https://www.ncbi.nlm.nih.gov/pubmed/35346832 http://dx.doi.org/10.1016/j.nbd.2022.105713

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