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Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA

Human DNA helicase B (HELB) is a poorly characterized helicase suggested to play both positive and negative regulatory roles in DNA replication and recombination. In this work, we used bulk and single-molecule approaches to characterize the biochemical activities of HELB protein with a particular fo...

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Detalles Bibliográficos
Autores principales: Hormeno, Silvia, Wilkinson, Oliver J., Aicart-Ramos, Clara, Kuppa, Sahiti, Antony, Edwin, Dillingham, Mark S., Moreno-Herrero, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169624/
https://www.ncbi.nlm.nih.gov/pubmed/35385349
http://dx.doi.org/10.1073/pnas.2112376119