Pten heterozygosity restores neuronal morphology in fragile X syndrome mice

Genetic studies of hippocampal granule neuron development have been used to elucidate cellular functions of Pten and Fmr1. While mutations in each gene cause neurodevelopmental disorders such as autism and fragile X syndrome, how Pten and Fmr1 function alone or together during normal development is...

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Detalles Bibliográficos
Autores principales: Sathyanarayana, Shivaprasad H., Saunders, Jasmine A., Slaughter, Jacob, Tariq, Kamran, Chakrabarti, Rajarshi, Sadanandappa, Madhumala K., Luikart, Bryan W., Bosco, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169627/
https://www.ncbi.nlm.nih.gov/pubmed/35394871
http://dx.doi.org/10.1073/pnas.2109448119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169627/
https://www.ncbi.nlm.nih.gov/pubmed/35394871
http://dx.doi.org/10.1073/pnas.2109448119

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