Cargando…
FKBP52 and FKBP51 differentially regulate the stability of estrogen receptor in breast cancer
Estrogen receptor α (ERα) is a transcription factor that induces cell proliferation and exhibits increased expression in a large subset of breast cancers. The molecular mechanisms underlying the up-regulation of ERα activity, however, remain poorly understood. We identified FK506-binding protein 52...
Autores principales: | Habara, Makoto, Sato, Yuki, Goshima, Takahiro, Sakurai, Masashi, Imai, Hiroyuki, Shimizu, Hideyuki, Katayama, Yuta, Hanaki, Shunsuke, Masaki, Takahiro, Morimoto, Masahiro, Nishikawa, Sayaka, Toyama, Tatsuya, Shimada, Midori |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169630/ https://www.ncbi.nlm.nih.gov/pubmed/35394865 http://dx.doi.org/10.1073/pnas.2110256119 |
Ejemplares similares
-
FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells
por: Maeda, Keisuke, et al.
Publicado: (2021) -
Impact of FKBP52 on cell proliferation and hormone‐dependent cancers
por: Hanaki, Shunsuke, et al.
Publicado: (2023) -
Biological Actions of the Hsp90-binding Immunophilins FKBP51 and FKBP52
por: Zgajnar, Nadia R., et al.
Publicado: (2019) -
Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52
por: Mustafi, Sourajit M., et al.
Publicado: (2014) -
Analysis of FK506, timcodar (VX-853) and FKBP51 and FKBP52 chaperones in control of glucocorticoid receptor activity and phosphorylation
por: Hinds, Terry D, et al.
Publicado: (2014)