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Monocyte-derived SDF1 supports optic nerve regeneration and alters retinal ganglion cells’ response to Pten deletion
Although mammalian retinal ganglion cells (RGCs) normally cannot regenerate axons nor survive after optic nerve injury, this failure is partially reversed by inducing sterile inflammation in the eye. Infiltrative myeloid cells express the axogenic protein oncomodulin (Ocm) but additional, as-yet-uni...
Autores principales: | Xie, Lili, Cen, Ling-Ping, Li, Yiqing, Gilbert, Hui-Ya, Strelko, Oleksandr, Berlinicke, Cynthia, Stavarache, Mihaela A., Ma, Madeline, Wang, Yongting, Cui, Qi, Kaplitt, Michael G., Zack, Donald J., Benowitz, Larry I., Yin, Yuqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169637/ https://www.ncbi.nlm.nih.gov/pubmed/35394873 http://dx.doi.org/10.1073/pnas.2113751119 |
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