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Monocyte-derived SDF1 supports optic nerve regeneration and alters retinal ganglion cells’ response to Pten deletion

Although mammalian retinal ganglion cells (RGCs) normally cannot regenerate axons nor survive after optic nerve injury, this failure is partially reversed by inducing sterile inflammation in the eye. Infiltrative myeloid cells express the axogenic protein oncomodulin (Ocm) but additional, as-yet-uni...

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Detalles Bibliográficos
Autores principales: Xie, Lili, Cen, Ling-Ping, Li, Yiqing, Gilbert, Hui-Ya, Strelko, Oleksandr, Berlinicke, Cynthia, Stavarache, Mihaela A., Ma, Madeline, Wang, Yongting, Cui, Qi, Kaplitt, Michael G., Zack, Donald J., Benowitz, Larry I., Yin, Yuqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169637/
https://www.ncbi.nlm.nih.gov/pubmed/35394873
http://dx.doi.org/10.1073/pnas.2113751119

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