PET imaging of TSPO expression in immune cells can assess organ-level pathophysiology in high-consequence viral infections

Ebola virus (EBOV) disease is characterized by lymphopenia, breach in vascular integrity, cytokine storm, and multiorgan failure. The pathophysiology of organ involvement, however, is incompletely understood. Using [(18)F]-DPA-714 positron emission tomography (PET) imaging targeting the translocator...

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Detalles Bibliográficos
Autores principales: Shah, Swati, Sinharay, Sanhita, Patel, Reema, Solomon, Jeffrey, Lee, Ji Hyun, Schreiber-Stainthorp, William, Basuli, Falguni, Zhang, Xiang, Hagen, Katie R., Reeder, Rebecca, Wakim, Paul, Huzella, Louis M., Maric, Dragan, Johnson, Reed F., Hammoud, Dima A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169664/
https://www.ncbi.nlm.nih.gov/pubmed/35385353
http://dx.doi.org/10.1073/pnas.2110846119

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