TCR-mimic bispecific antibodies to target the HIV-1 reservoir

HIV-1 infection is incurable due to the persistence of the virus in a latent reservoir of resting memory CD4(+) T cells. “Shock-and-kill” approaches that seek to induce HIV-1 gene expression, protein production, and subsequent targeting by the host immune system have been unsuccessful due to a lack...

Descripción completa

Detalles Bibliográficos
Autores principales: Sengupta, Srona, Board, Nathan L., Wu, Fengting, Moskovljevic, Milica, Douglass, Jacqueline, Zhang, Josephine, Reinhold, Bruce R., Duke-Cohan, Jonathan, Yu, Jeanna, Reed, Madison C., Tabdili, Yasmine, Azurmendi, Aitana, Fray, Emily J., Zhang, Hao, Hsiue, Emily Han-Chung, Jenike, Katharine, Ho, Ya-Chi, Gabelli, Sandra B., Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin, Siliciano, Janet D., Sadegh-Nasseri, Scheherazade, Reinherz, Ellis L., Siliciano, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169739/
https://www.ncbi.nlm.nih.gov/pubmed/35394875
http://dx.doi.org/10.1073/pnas.2123406119

Ejemplares similares

Ejemplares similares