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Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle

Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) challenge currently available COVID-19 vaccines and monoclonal antibody therapies due to structural and dynamic changes of the viral spike glycoprotein (S). The heptad repeat 1 (HR1) and heptad repeat 2 (HR2) domains of S drive...

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Detalles Bibliográficos
Autores principales:	Yang, Kailu, Wang, Chuchu, White, K. Ian, Pfuetzner, Richard A., Esquivies, Luis, Brunger, Axel T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169775/ https://www.ncbi.nlm.nih.gov/pubmed/35363556 http://dx.doi.org/10.1073/pnas.2119467119

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