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Toxicities and Response Rates of Secondary CNS Lymphoma After Adoptive Immunotherapy With CD19-Directed Chimeric Antigen Receptor T Cells

BACKGROUND AND OBJECTIVES: Secondary CNS involvement in systemic B-cell lymphoma (SCNSL) is difficult to treat and displays dismal clinical outcomes. Chimeric antigen receptor (CAR) T cells emerged as a powerful treatment for systemic lymphoma. We aimed to evaluate whether CAR T cells also represent...

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Detalles Bibliográficos
Autores principales: Karschnia, Philipp, Rejeski, Kai, Winkelmann, Michael, Schöberl, Florian, Bücklein, Veit L., Blumenberg, Viktoria, Schmidt, Christian, Blobner, Jens, von Bergwelt-Baildon, Michael, Tonn, Joerg-Christian, Kunz, Wolfgang G., Subklewe, Marion, von Baumgarten, Louisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169944/
https://www.ncbi.nlm.nih.gov/pubmed/35351785
http://dx.doi.org/10.1212/WNL.0000000000200608

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