MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection

CD8 T cells mediate protection against intracellular pathogens and tumors. However, persistent antigen during chronic infections or cancer leads to T cell exhaustion, suboptimal functionality, and reduced protective capacity. Despite considerable work interrogating the transcriptional regulation of...

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Detalles Bibliográficos
Autores principales: Stelekati, Erietta, Cai, Zhangying, Manne, Sasikanth, Chen, Zeyu, Beltra, Jean-Christophe, Buchness, Lance Alec, Leng, Xuebing, Ristin, Svetlana, Nzingha, Kito, Ekshyyan, Viktoriya, Niavi, Christina, Abdel-Hakeem, Mohamed S., Ali, Mohammed-Alkhatim, Drury, Sydney, Lau, Chi Wai, Gao, Zhen, Ban, Yuguang, Zhou, Simon K., Ansel, K. Mark, Kurachi, Makoto, Jordan, Martha S., Villarino, Alejandro V., Ngiow, Shin Foong, Wherry, E. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169946/
https://www.ncbi.nlm.nih.gov/pubmed/35446623
http://dx.doi.org/10.1073/pnas.2106083119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169946/
https://www.ncbi.nlm.nih.gov/pubmed/35446623
http://dx.doi.org/10.1073/pnas.2106083119

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