Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole-cell mechanics

The ability of a cell to regulate its mechanical properties is central to its function. Emerging evidence suggests that interactions between the cell nucleus and cytoskeleton influence cell mechanics through poorly understood mechanisms. Here we conduct quantitative confocal imaging to show that the...

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Detalles Bibliográficos
Autores principales: Vahabikashi, Amir, Sivagurunathan, Suganya, Nicdao, Fiona Ann Sadsad, Han, Yu Long, Park, Chan Young, Kittisopikul, Mark, Wong, Xianrong, Tran, Joseph R., Gundersen, Gregg G., Reddy, Karen L., Luxton, G. W. Gant, Guo, Ming, Fredberg, Jeffrey J., Zheng, Yixian, Adam, Stephen A., Goldman, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170021/
https://www.ncbi.nlm.nih.gov/pubmed/35439057
http://dx.doi.org/10.1073/pnas.2121816119

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