Cargando…

Postmitotic G1 phase survivin drives mitogen-independent cell division of B lymphocytes

B and T lymphocytes of the adaptive immune system undergo proliferative bursts to generate pools of antigen-specific cells for effective immunity. Here we show that in contrast to the canonical view that G1 progression signals are essential after mitosis to reenter S phase, B lymphocytes sustain sev...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Amit, Spitzer, Matthew H., Joy, Jaimy P., Kaileh, Mary, Qiu, Xiang, Nolan, Garry P., Sen, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170024/
https://www.ncbi.nlm.nih.gov/pubmed/35476510
http://dx.doi.org/10.1073/pnas.2115567119