Cargando…
Studies on enmetazobactam clarify mechanisms of widely used β-lactamase inhibitors
β-Lactams are the most important class of antibacterials, but their use is increasingly compromised by resistance, most importantly via serine β-lactamase (SBL)-catalyzed hydrolysis. The scope of β-lactam antibacterial activity can be substantially extended by coadministration with a penicillin-deri...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170034/ https://www.ncbi.nlm.nih.gov/pubmed/35486701 http://dx.doi.org/10.1073/pnas.2117310119 |