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Generation of double Holliday junction DNAs and their dissolution/resolution within a chromatin context
Four-way DNA intermediates, also known as Holliday junctions (HJs), are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation. To facilitate the biochemical analysis of HJ processing, we developed a method involving DNAzyme self-cl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170140/ https://www.ncbi.nlm.nih.gov/pubmed/35452329 http://dx.doi.org/10.1073/pnas.2123420119 |