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An antagonistic pleiotropic gene regulates the reproduction and longevity tradeoff

The antagonistic pleiotropy theory of aging proposes that genes enhancing fitness in early life limit the lifespan, but the molecular evidence remains underexplored. By profiling translatome changes in Caenorhabditis elegans during starvation recovery, we find that an open reading frame (ORF) trl-1...

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Detalles Bibliográficos
Autores principales:	Wu, Dou, Wang, Zi, Huang, Jingying, Huang, Liang, Zhang, Songbo, Zhao, Ruixue, Li, Wei, Chen, Di, Ou, Guangshuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170148/ https://www.ncbi.nlm.nih.gov/pubmed/35482917 http://dx.doi.org/10.1073/pnas.2120311119

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