Dcp2 C-terminal cis-binding elements control selective targeting of the decapping enzyme by forming distinct decapping complexes

A single Dcp1–Dcp2 decapping enzyme targets diverse classes of yeast mRNAs for decapping-dependent 5′ to 3′ decay, but the molecular mechanisms controlling mRNA selectivity by the enzyme remain elusive. Through extensive genetic analyses we reveal that Dcp2 C-terminal domain cis-regulatory elements...

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Detalles Bibliográficos
Autores principales: He, Feng, Wu, Chan, Jacobson, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170289/
https://www.ncbi.nlm.nih.gov/pubmed/35604319
http://dx.doi.org/10.7554/eLife.74410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170289/
https://www.ncbi.nlm.nih.gov/pubmed/35604319
http://dx.doi.org/10.7554/eLife.74410

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