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A curcumin-based AIEE-active fluorescent probe for Cu(2+) detection in aqueous solution

Curcuminoids have been extensively investigated as metal ion probes, but the intrinsic aggregation-caused-quenching (ACQ) characteristic of curcumin would hinder their applications in aqueous solution. Fortunately, tetraphenylethylene (TPE) could endow the compounds with aggregation-induced emission...

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Autores principales: Lin, Yang, Yu, Ao, Wang, Jinjing, Kong, Derui, Liu, Hongtao, Li, Jianwei, Jia, Chunman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170379/
https://www.ncbi.nlm.nih.gov/pubmed/35754898
http://dx.doi.org/10.1039/d2ra02595g
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author Lin, Yang
Yu, Ao
Wang, Jinjing
Kong, Derui
Liu, Hongtao
Li, Jianwei
Jia, Chunman
author_facet Lin, Yang
Yu, Ao
Wang, Jinjing
Kong, Derui
Liu, Hongtao
Li, Jianwei
Jia, Chunman
author_sort Lin, Yang
collection PubMed
description Curcuminoids have been extensively investigated as metal ion probes, but the intrinsic aggregation-caused-quenching (ACQ) characteristic of curcumin would hinder their applications in aqueous solution. Fortunately, tetraphenylethylene (TPE) could endow the compounds with aggregation-induced emission (AIE)/aggregation-induced enhanced emission (AIEE) characteristics to eliminate the ACQ effect. According to this strategy, a series of TPE-modified curcumin derivatives L1–4 were prepared and studied for their AIEE properties. Among the four TPE-curcumin analogues, only L1 particles have been successfully used as an on-off fluorescence probe for detecting Cu(2+) in aqueous solution. The fluorescence titration experiment determined its detection limit of 1.49 × 10(−7) mol L(−1), and the binding ratio between L1 and Cu(2+) was estimated as 2 : 1, which was in agreement with the results of high resolution mass spectrum and Job's plot. In addition, the binding constant was evaluated as 6.77 × 10(2) M(−1) using a Benesi–Hildebrand plot. Finally, the obtained L1-based indicator paper showed significant fluorescence response to Cu(2+) aqueous solution. This TPE-modified strategy improves the detection capability of curcumin probe in aqueous solution and provides a feasible way to obtain other probes with ACQ characteristics.
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spelling pubmed-91703792022-06-23 A curcumin-based AIEE-active fluorescent probe for Cu(2+) detection in aqueous solution Lin, Yang Yu, Ao Wang, Jinjing Kong, Derui Liu, Hongtao Li, Jianwei Jia, Chunman RSC Adv Chemistry Curcuminoids have been extensively investigated as metal ion probes, but the intrinsic aggregation-caused-quenching (ACQ) characteristic of curcumin would hinder their applications in aqueous solution. Fortunately, tetraphenylethylene (TPE) could endow the compounds with aggregation-induced emission (AIE)/aggregation-induced enhanced emission (AIEE) characteristics to eliminate the ACQ effect. According to this strategy, a series of TPE-modified curcumin derivatives L1–4 were prepared and studied for their AIEE properties. Among the four TPE-curcumin analogues, only L1 particles have been successfully used as an on-off fluorescence probe for detecting Cu(2+) in aqueous solution. The fluorescence titration experiment determined its detection limit of 1.49 × 10(−7) mol L(−1), and the binding ratio between L1 and Cu(2+) was estimated as 2 : 1, which was in agreement with the results of high resolution mass spectrum and Job's plot. In addition, the binding constant was evaluated as 6.77 × 10(2) M(−1) using a Benesi–Hildebrand plot. Finally, the obtained L1-based indicator paper showed significant fluorescence response to Cu(2+) aqueous solution. This TPE-modified strategy improves the detection capability of curcumin probe in aqueous solution and provides a feasible way to obtain other probes with ACQ characteristics. The Royal Society of Chemistry 2022-06-07 /pmc/articles/PMC9170379/ /pubmed/35754898 http://dx.doi.org/10.1039/d2ra02595g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Lin, Yang
Yu, Ao
Wang, Jinjing
Kong, Derui
Liu, Hongtao
Li, Jianwei
Jia, Chunman
A curcumin-based AIEE-active fluorescent probe for Cu(2+) detection in aqueous solution
title A curcumin-based AIEE-active fluorescent probe for Cu(2+) detection in aqueous solution
title_full A curcumin-based AIEE-active fluorescent probe for Cu(2+) detection in aqueous solution
title_fullStr A curcumin-based AIEE-active fluorescent probe for Cu(2+) detection in aqueous solution
title_full_unstemmed A curcumin-based AIEE-active fluorescent probe for Cu(2+) detection in aqueous solution
title_short A curcumin-based AIEE-active fluorescent probe for Cu(2+) detection in aqueous solution
title_sort curcumin-based aiee-active fluorescent probe for cu(2+) detection in aqueous solution
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170379/
https://www.ncbi.nlm.nih.gov/pubmed/35754898
http://dx.doi.org/10.1039/d2ra02595g
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