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CD4(+) T helper 2 cells suppress breast cancer by inducing terminal differentiation
Cancer immunology research is largely focused on the role of cytotoxic immune responses against advanced cancers. Herein, we demonstrate that CD4(+) T helper (Th2) cells directly block spontaneous breast carcinogenesis by inducing the terminal differentiation of the cancer cells. Th2 cell immunity,...
Autores principales: | Boieri, Margherita, Malishkevich, Anna, Guennoun, Ranya, Marchese, Emanuela, Kroon, Sanne, Trerice, Kathryn E., Awad, Mary, Park, Jong Ho, Iyer, Sowmya, Kreuzer, Johannes, Haas, Wilhelm, Rivera, Miguel N., Demehri, Shadmehr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170526/ https://www.ncbi.nlm.nih.gov/pubmed/35657353 http://dx.doi.org/10.1084/jem.20201963 |
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