Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity

The integral membrane, Kunitz-type serine protease inhibitors HAI-1 and HAI-2, can suppress the proteolytic activity of the type 2 transmembrane serine protease matriptase with high specificity and potency. High levels of extracellular matriptase proteolytic activity have, however, been observed in...

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Detalles Bibliográficos
Autores principales: Chiu, Yi-Lin, Wu, Yi-Ying, Barndt, Robert B., Lin, Yu-Wen, Sytwo, Hou-Ping, Cheng, Amy, Yang, Kacy, Chan, Khee-Siang, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170578/
https://www.ncbi.nlm.nih.gov/pubmed/35685459
http://dx.doi.org/10.1016/j.gendis.2020.12.001

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