The drug-induced phenotypic landscape of colorectal cancer organoids

Patient-derived organoids resemble the biology of tissues and tumors, enabling ex vivo modeling of human diseases. They have heterogeneous morphologies with unclear biological causes and relationship to treatment response. Here, we use high-throughput, image-based profiling to quantify phenotypes of...

Descripción completa

Detalles Bibliográficos
Autores principales: Betge, Johannes, Rindtorff, Niklas, Sauer, Jan, Rauscher, Benedikt, Dingert, Clara, Gaitantzi, Haristi, Herweck, Frank, Srour-Mhanna, Kauthar, Miersch, Thilo, Valentini, Erica, Boonekamp, Kim E., Hauber, Veronika, Gutting, Tobias, Frank, Larissa, Belle, Sebastian, Gaiser, Timo, Buchholz, Inga, Jesenofsky, Ralf, Härtel, Nicolai, Zhan, Tianzuo, Fischer, Bernd, Breitkopf-Heinlein, Katja, Burgermeister, Elke, Ebert, Matthias P., Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170716/
https://www.ncbi.nlm.nih.gov/pubmed/35668108
http://dx.doi.org/10.1038/s41467-022-30722-9

Ejemplares similares

Ejemplares similares