Tetracycline response element driven Cre causes ectopic recombinase activity independent of transactivator element

OBJECTIVE: Tamoxifen is widely used for inducible Cre-LoxP systems but has several undesirable side effects for researchers investigating metabolism or energy balance, including weight loss, lipoatrophy, and drug incorporation into lipid stores. For this reason, we sought to determine whether a doxy...

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Detalles Bibliográficos
Autores principales: Lewis, Kenneth T., Oles, Lily R., MacDougald, Ormond A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170755/
https://www.ncbi.nlm.nih.gov/pubmed/35452876
http://dx.doi.org/10.1016/j.molmet.2022.101501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170755/
https://www.ncbi.nlm.nih.gov/pubmed/35452876
http://dx.doi.org/10.1016/j.molmet.2022.101501

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