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Tetracycline response element driven Cre causes ectopic recombinase activity independent of transactivator element
OBJECTIVE: Tamoxifen is widely used for inducible Cre-LoxP systems but has several undesirable side effects for researchers investigating metabolism or energy balance, including weight loss, lipoatrophy, and drug incorporation into lipid stores. For this reason, we sought to determine whether a doxy...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170755/ https://www.ncbi.nlm.nih.gov/pubmed/35452876 http://dx.doi.org/10.1016/j.molmet.2022.101501 |