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Treatment of arterial calcification in patients with chronic limb threatening ischemia with etidronate: protocol of an investigator-initiated multicenter, double blind, placebo-controlled, randomized clinical trial
BACKGROUND: Pathologic studies have shown that in patients with critical limb threatening ischaemia (CLTI) medial arterial calcifications are frequently found and may be responsible for aggravating the disease. These extensive calcifitcations are found not only in arteries of the leg but also in the...
Autores principales: | Hoogervorst, R., van Overhagen, H., de Jong, P. A., Spiering, W., de Borst, G. J., Veger, H. T. C., Mairuhu, A. T. A., Mali, W. P. T. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170866/ https://www.ncbi.nlm.nih.gov/pubmed/35666322 http://dx.doi.org/10.1186/s42155-022-00298-y |
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