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Modulation of the Thrombin Pathway Restores LTP in a Pilocarpine Mice Model of Status Epilepticus

BACKGROUND: Status epilepticus (SE) leads to memory impairment following a seizure, attributed to long-term potentiation (LTP) reduction. Thrombin, a coagulation factor that activates protease-activated receptor 1 (PAR1) is involved in cognitive impairment following traumatic brain injury by reducin...

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Detalles Bibliográficos
Autores principales:	Shavit-Stein, Efrat, Berkowitz, Shani, Davidy, Tal, Fennig, Uri, Gofrit, Shani Guly, Dori, Amir, Maggio, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170943/ https://www.ncbi.nlm.nih.gov/pubmed/35685989 http://dx.doi.org/10.3389/fncel.2022.900925

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